CompareGeneral OperationAğustos 1516 - January 1517Ottoman–Mamluk War (1516–1517)★ Ottoman Empire Army%78Mamluk Sultanate Army%22OttomanTurkishVSMamlukCircassian
CompareGeneral Operation1518 - 1658Sinhalese–Portuguese ConflictsPortuguese Empire Ceylon Forces%58★ Sinhalese Kingdoms Coalition (Kotte, Sitawaka, Kandy)%42PortugalPortugueseVSSinhalese KingdomsSinhalese
CompareGeneral OperationAralık 1519 - 5 April 1521Polish–Teutonic War (Rider's War) 1519–1521★ Kingdom of Poland Forces%63Teutonic Order Monastic State%37PolandPolishVSTeutonic Order StateGerman
CompareGeneral OperationŞubat 1519 - 13 Ağustos 1521Spanish Conquest of the Aztec Empire★ Spanish-Tlaxcalan Coalition%34Aztec Triple Alliance%66SpainSpanishVSAztec EmpireNahua
CompareGeneral Operation1519 - 1523Revolt of the Brotherhoods (Germanías)Germanías (Guild Confederation) - Council of Thirteen%37★ Royal and Aristocratic Alliance (Forces of Charles V)%63Kingdom of Aragon (Rebel Guilds)Valencian (Catalan-Aragonese)VSSpain (Monarchy of Charles V)Castilian
CompareGeneral Operation1519 - 1610Jelali Revolts★ Ottoman Central Forces (Kapikulu Corps and Grand Vizier's Army)%63Jelali Rebel Coalition (Sekban-Levend-Suhte-Turkmen Bands)%37OttomanTurkishVSOttomanTurkish
CompareGeneral Operation16 April 1520 - 25 October 1521Revolt of the Comuneros (War of the Communities of Castile)Castilian Comuneros Army%43★ Royal Habsburg Forces%57Castilian CommunesCastilianVSHabsburg SpainCastilian
CompareGeneral OperationJanuary 1521 - 1 Eylül 1524Swedish War of Liberation★ Swedish Rebel Forces%38Kalmar Union (Kingdom of Denmark)%62SwedenSwedishVSDenmarkDanish
CompareGeneral Operation1521 - 1526Italian War of 1521–1526 (Four Years' War)Kingdom of France and Republic of Venice Alliance%43★ Holy Roman Empire, Spain, England and Papal Coalition%57FranceFrenchVSHoly Roman EmpireGermanic-Spanish
CompareGeneral Operation27 Ağustos 1522 - 6 Mayıs 1523Knights' Revolt (Imperial Knights' Uprising)Brotherly Convention (Imperial Knights' Coalition)%31★ Trier-Palatinate-Hesse Princes' Coalition%69Imperial Knights ConfederationGermanVSHoly Roman Empire (Princes' Coalition)German
CompareNaval BattleApril-Mayıs 1521Battle of Tunmen★ Ming Imperial Navy%73Portuguese Fleet%27Ming ChinaHanVSPortugalPortuguese
CompareSiege26 June - 22 Aralık 1522Siege of Rhodes (1522)★ Ottoman Imperial Army and Navy%76Knights Hospitaller of Saint John and Rhodes Defenders%24OttomanTurkishVSKnights HospitallerLatin